Associate Professor, National Neuroscience Institute, Singapore
🧠 Dr. Zeng Li is a renowned Senior Research Scientist and Principal Investigator at the National Neuroscience Institute, Singapore. With a strong background in biochemistry and molecular biology, Dr. Li has made significant contributions to understanding neurodegenerative diseases, particularly Alzheimer’s and Parkinson’s diseases. Her research focuses on translational studies, exploring the pathophysiology and potential therapeutic targets for these diseases.
Profile
scholar
🎓 Education
📚 Dr. Li holds a (link unavailable) in Biology from Beijing Normal University, China (1992), and a Ph.D. in Biochemistry from the University of Glasgow, UK (1996). Her academic background has provided a solid foundation for her research career.
👨🔬 Experience
💼 Dr. Li has over two decades of research experience, including postdoctoral training in signal transduction and developmental biology at the Institute of Molecular and Cell Biology, A*STAR. She joined the National Neuroscience Institute in 2009, where she has been leading her research team, focusing on neurodegenerative diseases.
🔍 Research Interest
🔬 Dr. Li’s research focuses on understanding the molecular mechanisms underlying neurodegenerative diseases, particularly Alzheimer’s and Parkinson’s diseases. Her team explores the role of specific genes and microRNAs in disease progression and investigates potential therapeutic targets. They also use 3D cerebral organoids and induced pluripotent stem cells to model disease phenotypes.
Awards and Honors🏆
🏆 Dr. Li has received several awards for her research, including the Best Publish Award from the National Neuroscience Institute (2017 and 2022). Her work has been featured in prominent media outlets, such as The Straits Times and Globe Newswire, highlighting the impact of her research.
📚 Publications
1. Tu H, et al. NOTCH2NLC GGC intermediate repeat with serine induces hypermyelination and early Parkinson’s disease-like phenotypes in mice. Mol. Neurodegener. 2024.
2. Jiang M, et al. The Effects of Extrinsic and Intrinsic Factors on Neurogenesis. Cells 2023.
3. Long YH, et al. Spatially informed clustering, integration, and deconvolution of spatial transcriptomics with GraphST. Nature Communication. 2023.
4. Kumar P, et al. Single-cell transcriptomics and surface epitope detection in human brain epileptic lesions identifies pro-inflammatory signaling. Nat Neurosci. 2022.
5. Zhang ZW, et al. APP Intracellular Domain Promotes Expression of LRRK2 Enabling a Feed-Forward Loop of Neurodegeneration in Parkinson’s Disease. Sci Signal 2022.
Conclusion
Dr. Zeng Li is an outstanding researcher in the field of neuroscience, with a strong track record of innovative research contributions and high-impact publications. Her dedication to translational research and collaboration with clinicians has the potential to transform our understanding of neurodegenerative diseases. With some additional focus on public engagement and mentorship, Dr. Li is an excellent candidate for the Best Researcher Award.